Pulmonary capillary leak syndrome associated with the use of intravenous cyclosporin.

نویسندگان

  • M M Hussein
  • J M Mooij
  • A M el Tayeb
چکیده

Pulmonary oedema due to pulmonary capillary leak syndrome during the use of cyclosporin, particularly when given intravenously, has been reported in some patients after bone marrow, liver, and renal transplantation [1-4]. Suggested explanations for this effect have been a local high concentration of the drug in the pulmonary vessels when infused through a central line [3], or the solvent polyoxyethylated castor oil in the parenteral formulation of cyclosporin [4]. However, this side-effect is not widely known and not listed in the drug information supplied by the company [5]. We report here on a patient who, after living-related transplantation, developed pulmonary oedema due to capillary leak syndrome that improved after converting from intravenous to oral cyclosporin.

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عنوان ژورنال:
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

دوره 11 11  شماره 

صفحات  -

تاریخ انتشار 1996