Pulmonary capillary leak syndrome associated with the use of intravenous cyclosporin.
نویسندگان
چکیده
Pulmonary oedema due to pulmonary capillary leak syndrome during the use of cyclosporin, particularly when given intravenously, has been reported in some patients after bone marrow, liver, and renal transplantation [1-4]. Suggested explanations for this effect have been a local high concentration of the drug in the pulmonary vessels when infused through a central line [3], or the solvent polyoxyethylated castor oil in the parenteral formulation of cyclosporin [4]. However, this side-effect is not widely known and not listed in the drug information supplied by the company [5]. We report here on a patient who, after living-related transplantation, developed pulmonary oedema due to capillary leak syndrome that improved after converting from intravenous to oral cyclosporin.
منابع مشابه
[May-Thurner syndrome: an infrequent cause of spontaneous left iliac vein rupture].
1. Druey KM, Greipp PR. Narrative review: The systemic capillary leak syndrome. Ann Intern Med. 2010;153:90--8. 2. Kapoor P, Greipp PT, Schaefer EW, Mandrekar SJ, Kamal AH, Gonzalez-Paz NC, et al. Idiopathic systemic capillary leak syndrome (Clarkson’s Disease): The Mayo Clinic Experience. Mayo Clin Proc. 2010;85:905--12. 3. Gousseff M, Arnaud L, Lambert M, Hot A, Hamidou M, Duhaut P, et al. Th...
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ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 11 11 شماره
صفحات -
تاریخ انتشار 1996